RHUGM-CSF-50µg GENTAUR HEADQUARTERS +32 1641 4407 +32 1650 9045
Molgramostim is a human granulocyte macrophage colony-stimulating factor (GM-CSF), produced by recombinant DNA technology from E.coli. It is 127 amino acid protein, non-glycosylated, and has a molecular weight of approximately 14.5kD. The amino acid sequence is identical to the natural, except for the addition of an N-terminal methionine.
1. In patients receiving myelosuppressive therapy ( cancer chemotherapy ) to reduce the severity of neutropenia, thereby reducing the risk of infection and allowing better adherence to the chemotherapeutic regimen;
2. In patients undergoing autologous or syngeneic bone marrow transplantation to accelerate myeloid recovery (Molgramostim does not improve overall survival or increase time to relapse);
l Pharmaceutical particulars
Sterile, white and preservative-free lyophilized powder to be reconstituted with a diluent (Sterile Water for Injection) for injection, presented in vials.
Dosage: 75μg/vial, 150μg/vial, 300μg/vial and 400μg/vial
Reference: Current European Pharmacopoeia and Internal Requirements
Specific activity: ≥1.0×107IU/mg
Purity (HPLC, SDS-PAGE): ≥98%
Active ingredients: Molgramostim (rHuGM-CSF)
Inactive ingredients: Mannitol, Macrogol 4000, Human Albumin, Dibasic Sodium phosphate and Monobasic Potassium Phosphate.
l Shelf life and storage conditions
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